Handbook On Opium: History And Basis Of Opioids In Therapeutics

Explore the intricate world of opium and opioids with the “Handbook on Opium: History and Basis of Opioids in Therapeutics.” This comprehensive guide delves into the historical significance of opium, tracing its use from ancient civilizations to its modern-day applications in medicine. Gain a deep understanding of the chemical composition of opium and how its various alkaloids, such as morphine and codeine, interact with the human body to produce analgesic and other therapeutic effects. The book thoroughly examines the pharmacological basis of opioids, exploring their mechanisms of action on opioid receptors and their impact on pain pathways. It also provides insights into the development of semi-synthetic and synthetic opioids, highlighting the ongoing research efforts to create safer and more effective pain relievers. Furthermore, the handbook addresses the challenges associated with opioid use, including tolerance, dependence, and addiction, offering a balanced perspective on the risks and benefits of opioid therapy. Clinicians, researchers, and students alike will find this handbook an invaluable resource for navigating the complex landscape of opioids in therapeutics.